Analysis of completed US phase 3 clinical trials (n=5051) registered at ClinicalTrials.gov (first received: 01/01/2002 to 01/01/2014)

Version 4 2014-07-30, 06:28

Version 3 2014-07-30, 06:28

Version 2 2014-07-24, 01:09

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dataset

posted on 2014-07-30, 06:28 authored by Jorge H RamirezJorge H Ramirez, Mauricio PalaciosMauricio Palacios

"The majority of US phase 3 trials were retrospectively registered. Only three out of ten studies that were completed before January 2011 have results available, data was submitted to ClinicalTrials.gov within12 months by 34% of the investigators." (1)

Analysis of unpublished studies follows (infographics). (2)

Current number of completed US phase 3 trials (registered between 2002-2014)

1. Clinical trials with results and without results

Intervention = drug | URL: http://goo.gl/s0JciJ
Intervention = biological | URL: http://goo.gl/ARQFnJ

2. Clinical trials with results

Intervention = drug | URL: http://goo.gl/s0JciJ
Intervention = biological | URL: http://goo.gl/ARQFnJ

References

1. Ramirez JH, Palacios M. Re: The US requirement to deposit trial data within a year is unworkable. March 17, 2014. URL: http://www.bmj.com/node/753103

2. Ramirez, Jorge H (2014): Infographics: Unpublished US phase 3 clinical trials (2002-2012) completed before Jan 2011 = 50.8%. figshare.
http://dx.doi.org/10.6084/m9.figshare.1121675Retrieved 23:05, Jul 30, 2014 (GMT)

This database complies with the terms and conditions of ClinicalTrials.gov (http://clinicaltrials.gov/ct2/about-site/terms-conditions) and the WHO ICTRP (http://www.who.int/ictrp/search/download/en/) for using downloaded data.